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diabetic kidney disease 3

diabetic nephropathy 3

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Clinical characteristics and outcomes of biopsy-proven diabetic nephropathy

Li Zhuo, Nianrong Zhang, Guming Zou, Dapeng Chen, Wenge Li

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 386-392 doi: 10.1007/s11684-017-0574-z

Abstract: Predictive factors for diabetic nephropathy (DN) outcomes are also poorly understood.Diabetic retinopathy (78.4%) was a crucial complication in patients with DN.

Keywords： diabetic nephropathy     clinical characteristics     renal biopsy     outcomes    

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Non-genetic mechanisms of diabetic nephropathy

Qiuxia Han, Hanyu Zhu, Xiangmei Chen, Zhangsuo Liu

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 319-332 doi: 10.1007/s11684-017-0569-9

Abstract:

Diabetic nephropathy (DN) is one of the most common microvascular complications in diabetes mellitus

Keywords： diabetic nephropathy     immune inflammatory response     epithelial–mesenchymal transition     apoptosis     mitochondrial    

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Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells

Biqiong Fu, Jie Yang, Jia Chen, Lirong Lin, Kehong Chen, Weiwei Zhang, Jianguo Zhang, Yani He

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 267-276 doi: 10.1007/s11684-017-0586-8

Abstract: be a novel strategy for protecting against HG-induced renal tubular cell senescence in treatment of diabeticnephropathy.

Keywords： Shenkang injection     senescence     renal tubular epithelial cells     diabetic nephropathy    

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Hyperglycemic memory in diabetic cardiomyopathy

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 25-38 doi: 10.1007/s11684-021-0881-2

Abstract: Cardiovascular diseases account for approximately 80% of deaths among individuals with diabetes mellitus, with diabeticcardiomyopathy as the major diabetic cardiovascular complication.herein the current advances that have been achieved in research on the underlying mechanisms of HGM in diabetic

Keywords： diabetes     diabetic cardiomyopathy     hyperglycemic memory    

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DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese

Wei Wang,Ming Li,Li Wang,Xueqing Yu

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 507-516 doi: 10.1007/s11684-016-0475-6

Abstract:

Immunoglobulin A nephropathy (IgAN) is a common form of chronic glomerulonephritis with unknown pathogenesis

Keywords： DQB1     human leukocyte antigen (HLA)     IgA nephropathy     haplotype     association study    

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Normoalbuminuric diabetic kidney disease

Chao Chen, Chang Wang, Chun Hu, Yachun Han, Li Zhao, Xuejing Zhu, Li Xiao, Lin Sun

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 310-318 doi: 10.1007/s11684-017-0542-7

Abstract:

Diabetic kidney disease (DKD) is one of the primary causes of end-stage renal disease (ESRD).patients with normoalbuminuria have progressive renal insufficiency, referred to as normoalbuminuric diabetickidney disease (NADKD) or nonalbuminuric diabetic nephropathy.Epidemiologic research has demonstrated that normoalbuminuric diabetic kidney disease is common, and

Keywords： diabetes     diabetic kidney disease     normoalbuminuria     renal impairment    

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Carbon dots-based fluorescence sensor for two-photon imaging of pH in diabetic mice

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 3,   Pages 298-306 doi: 10.1007/s11705-022-2212-9

Abstract: Finally, the CA-CDs has been successfully applied for two-photon imaging of the pH in liver and kidney of diabeticImaging results showed that the pH value in kidney of diabetic mice was lower than that of the normalmice, while the pH value in liver of diabetic mice was almost the same as that of the normal mice.

Keywords： carbon dots     two-photon imaging     pH     diabetic mice    

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Comparative analysis of membranous and other nephropathy subtypes and establishment of a diagnostic model

Hanyu Zhu, Bo Fu, Yong Wang, Jing Gao, Qiuxia Han, Wenjia Geng, Xiaoli Yang, Guangyan Cai, Xiangmei Chen, Dong Zhang

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 618-625 doi: 10.1007/s11684-018-0620-5

Abstract: This study aimed to compare clinical features between membranous nephropathy (MN) and nonmembranous nephropathy

Keywords： multiparameter analysis     diagnosis     model     membranous nephropathy    

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Adenovirus-mediated antisense ERK2 gene therapy ameliorates chronic allograft nephropathy in a rat model

Zhao DING, Zhishui CHEN, Xilin CHEN, Ming CAI, Hui GUO, Nianqiao GONG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 204-210 doi: 10.1007/s11684-009-0039-0

Abstract: underlying mechanism of adenovirus-mediated antisense ERK2 (Adanti-ERK2) gene therapy upon chronic allograft nephropathy

Keywords： anti-ERK2     renal transplantation     epithelial mesenchymal transition     chronic allograft nephropathy    

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Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease

Xiaojing Jiao, Dong Zhang, Quan Hong, Lei Yan, Qiuxia Han, Fengmin Shao, Guangyan Cai, Xiangmei Chen, Hanyu Zhu

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 293-304 doi: 10.1007/s11684-019-0715-7

Abstract: This study examined netrin-1 and UNC5B expression in kidneys with diabetic kidney disease (DKD) and investigated

Keywords： netrin-1     VEGF-165     UNC5B     angiogenesis     diabetic kidney disease    

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Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 301-305 doi: 10.1007/s11684-013-0283-1

Abstract: However, the sensitivity of the diabetic heart to IPostC is impaired and the underlying mechanism isAdiponectin (APN) is an adipocyte-derived plasma protein with anti-diabetic and anti-inflammatory propertiesHowever, the effect of APN on myocardial injury in diabetic subjects, especially its potential in restoringthe sensitivity of the diabetic heart to IPostC has not been investigated.In the current paper, we discussed the possible reasons why the myocardium of diabetic subjects loses

Keywords： adiponectin     ischemic post-conditioning     ischemia reperfusion injury     diabetes    

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Zinc homeostasis in the metabolic syndrome and diabetes

Xiao Miao, Weixia Sun, Yaowen Fu, Lining Miao, Lu Cai

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 31-52 doi: 10.1007/s11684-013-0251-9

Abstract: Zn dyshomeostasis always is related to certain disorders such as metabolic syndrome, diabetes and diabeticThe associations of Zn with metabolic syndrome, diabetes and diabetic complications, thus, stem fromwhether there is a clear cause-and-effect relationship of Zn with metabolic syndrome, diabetes, or diabeticIn fact, it is known that Zn deficiency is a common phenomenon in diabetic patients.Theoretically Zn supplementation should prevent the metabolic syndrome, diabetes, and diabetic complications

Keywords： zinc     zinc transporters     metallothionein     diabetes     diabetic complications     insulin resistance     antioxidant    

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Type 2 diabetic patients with non-alcoholic fatty liver disease exhibit significant haemorheological

Hui Dong, Fu’er Lu, Nan Wang, Xin Zou, Jingjing Rao

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 288-293 doi: 10.1007/s11684-011-0127-9

Abstract: Diabetic patients with NAFLD exhibited significant haemorheological abnormalities compared with patients

Keywords： diabetes mellitus     type 2     haemorheology     non-alcoholic fatty liver disease    

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value of fasting glucose on the risk of heart failure and left ventricular systolic dysfunction in non-diabetic

Hui Wang, Yang Zhang, Zhujun Shen, Ligang Fang, Zhenyu Liu, Shuyang Zhang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 70-78 doi: 10.1007/s11684-020-0749-x

Abstract: glucose (FBG) on the risk of heart failure (HF) and left ventricular systolic dysfunction (LVSD) in non-diabeticpercutaneous coronary intervention (PCI) for acute STEMI, we retrospectively recruited consecutive non-diabeticIn conclusion, elevated FBG was independently associated with 30-day HF and LVSD risk in non-diabetic

Keywords： myocardial infarction     percutaneous coronary intervention     diabetes mellitus     fasting glucose     heart failure    

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Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic

Jie Zheng,Yuzhen Gao,Yuejuan Jing,Xiaoshuang Zhou,Yuanyuan Shi,Yanhong Li,Lihua Wang,Ruiying Wang,Maolian Li,Chuanshi Xiao,Yafeng Li,Rongshan Li

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 477-483 doi: 10.1007/s11684-014-0346-y

Abstract: This cross-sectional study recruited 3460 non-diabetic Chinese subjects (1027 men, and 2433 women, agedthe first tertile with lower HDL-C level had a 1.75-fold increase in risk of IFG compared with non-diabeticIn Chinese non-diabetic women, dyslipidemia is independently associated with high levels of FPG; TG,

Keywords： dyslipidemia     plasma lipids     plasma fasting glucose     impaired fasting glucose     non-diabetes    

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Title Author Date Type Operation

Clinical characteristics and outcomes of biopsy-proven diabetic nephropathy

Li Zhuo, Nianrong Zhang, Guming Zou, Dapeng Chen, Wenge Li

Journal Article

Non-genetic mechanisms of diabetic nephropathy

Qiuxia Han, Hanyu Zhu, Xiangmei Chen, Zhangsuo Liu

Journal Article

Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells

Biqiong Fu, Jie Yang, Jia Chen, Lirong Lin, Kehong Chen, Weiwei Zhang, Jianguo Zhang, Yani He

Journal Article

Hyperglycemic memory in diabetic cardiomyopathy

Journal Article

DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese

Wei Wang,Ming Li,Li Wang,Xueqing Yu

Journal Article

Normoalbuminuric diabetic kidney disease

Chao Chen, Chang Wang, Chun Hu, Yachun Han, Li Zhao, Xuejing Zhu, Li Xiao, Lin Sun

Journal Article

Carbon dots-based fluorescence sensor for two-photon imaging of pH in diabetic mice

Journal Article

Comparative analysis of membranous and other nephropathy subtypes and establishment of a diagnostic model

Hanyu Zhu, Bo Fu, Yong Wang, Jing Gao, Qiuxia Han, Wenjia Geng, Xiaoli Yang, Guangyan Cai, Xiangmei Chen, Dong Zhang

Journal Article

Adenovirus-mediated antisense ERK2 gene therapy ameliorates chronic allograft nephropathy in a rat model

Zhao DING, Zhishui CHEN, Xilin CHEN, Ming CAI, Hui GUO, Nianqiao GONG

Journal Article

Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease

Xiaojing Jiao, Dong Zhang, Quan Hong, Lei Yan, Qiuxia Han, Fengmin Shao, Guangyan Cai, Xiangmei Chen, Hanyu Zhu

Journal Article

Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Journal Article

Zinc homeostasis in the metabolic syndrome and diabetes

Xiao Miao, Weixia Sun, Yaowen Fu, Lining Miao, Lu Cai

Journal Article

Type 2 diabetic patients with non-alcoholic fatty liver disease exhibit significant haemorheological

Hui Dong, Fu’er Lu, Nan Wang, Xin Zou, Jingjing Rao

Journal Article

value of fasting glucose on the risk of heart failure and left ventricular systolic dysfunction in non-diabetic

Hui Wang, Yang Zhang, Zhujun Shen, Ligang Fang, Zhenyu Liu, Shuyang Zhang

Journal Article

Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic

Jie Zheng,Yuzhen Gao,Yuejuan Jing,Xiaoshuang Zhou,Yuanyuan Shi,Yanhong Li,Lihua Wang,Ruiying Wang,Maolian Li,Chuanshi Xiao,Yafeng Li,Rongshan Li

Journal Article